BDBM50085272 5-Benzyl-2-(2-pyrrolidin-1-yl-ethoxy)-thiazole::CHEMBL163630

SMILES: C(CN1CCCC1)Oc1ncc(Cc2ccccc2)s1

InChI Key: InChIKey=AXDKPZDBKBTIER-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A4 hydrolase (Homo sapiens (Human))	BDBM50085272 (5-Benzyl-2-(2-pyrrolidin-1-yl-ethoxy)-thiazole | C...) Show SMILES C(CN1CCCC1)Oc1ncc(Cc2ccccc2)s1 Show InChI InChI=1S/C16H20N2OS/c1-2-6-14(7-3-1)12-15-13-17-16(20-15)19-11-10-18-8-4-5-9-18/h1-3,6-7,13H,4-5,8-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined against Leukotriene A4 hydrolase				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair
Leukotriene A4 hydrolase (Homo sapiens (Human))	BDBM50085272 (5-Benzyl-2-(2-pyrrolidin-1-yl-ethoxy)-thiazole | C...) Show SMILES C(CN1CCCC1)Oc1ncc(Cc2ccccc2)s1 Show InChI InChI=1S/C16H20N2OS/c1-2-6-14(7-3-1)12-15-13-17-16(20-15)19-11-10-18-8-4-5-9-18/h1-3,6-7,13H,4-5,8-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity was determined for LTB4 production in human whole blood.				J Med Chem 43: 721-35 (2000) BindingDB Entry DOI: 10.7270/Q2CN74MZ
					More data for this Ligand-Target Pair