BDBM50085594 CHEMBL3427702

SMILES: CCOC(CC(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1

InChI Key: InChIKey=PMWAAQCQJWJKES-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50085594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50085594 (CHEMBL3427702) Show SMILES CCOC(CC(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C18H18Cl2O4/c1-2-23-17(10-18(21)22)13-4-6-14(7-5-13)24-11-12-3-8-15(19)16(20)9-12/h3-9,17H,2,10-11H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in CHO cells assessed as increase in intracellular calcium level after 60 mins by FLIPR assay				Bioorg Med Chem 23: 5546-65 (2015) BindingDB Entry DOI: 10.7270/Q2K0762X
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50085594 (CHEMBL3427702) Show SMILES CCOC(CC(O)=O)c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C18H18Cl2O4/c1-2-23-17(10-18(21)22)13-4-6-14(7-5-13)24-11-12-3-8-15(19)16(20)9-12/h3-9,17H,2,10-11H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.20	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in CHO cells assessed as calcium flux by FLIPR assay				ACS Med Chem Lett 6: 266-70 (2015) Article DOI: 10.1021/ml500391n BindingDB Entry DOI: 10.7270/Q26T0PBH
					More data for this Ligand-Target Pair