BDBM50086116 CHEMBL3425700

SMILES: CC(C)(C)OC(=O)CNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12

InChI Key: InChIKey=BBSOZCBPHAAQLU-JLHYYAGUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086116 (CHEMBL3425700) Show SMILES CC(C)(C)OC(=O)CNc1nc(\C=C\c2ccc(Cl)cc2)nc2cc3ccccc3cc12 Show InChI InChI=1S/C26H24ClN3O2/c1-26(2,3)32-24(31)16-28-25-21-14-18-6-4-5-7-19(18)15-22(21)29-23(30-25)13-10-17-8-11-20(27)12-9-17/h4-15H,16H2,1-3H3,(H,28,29,30)/b13-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair