BDBM50086197 CHEMBL3425615

SMILES: CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)C1=CCCCC1

InChI Key: InChIKey=IFZJYINOMSGNCM-XNTDXEJSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50086197   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Escherichia coli)	BDBM50086197 (CHEMBL3425615) Show SMILES CN(C)CCNc1nc(\C=C\c2ccc(Cl)cc2)nc2ccc(cc12)C1=CCCCC1 |t:28| Show InChI InChI=1S/C26H29ClN4/c1-31(2)17-16-28-26-23-18-21(20-6-4-3-5-7-20)11-14-24(23)29-25(30-26)15-10-19-8-12-22(27)13-9-19/h6,8-15,18H,3-5,7,16-17H2,1-2H3,(H,28,29,30)/b15-10+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of Escherichia coli FtsZ GTPase activity after 5 mins by enzyme-coupled inhibition assay				ACS Med Chem Lett 6: 308-12 (2015) Article DOI: 10.1021/ml500497s BindingDB Entry DOI: 10.7270/Q2PV6N4C
					More data for this Ligand-Target Pair