BDBM50086344 4-Naphthalen-2-yl-piperidine-3-carboxylic acid methyl ester; hydrochloride::CHEMBL544209

SMILES: COC(=O)C1CNCC[C@H]1c1ccc2ccccc2c1

InChI Key: InChIKey=SFKHGLPGUQXRDS-VYRBHSGPSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50086344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50086344 (4-Naphthalen-2-yl-piperidine-3-carboxylic acid met...) Show SMILES COC(=O)C1CNCC[C@H]1c1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c1-20-17(19)16-11-18-9-8-15(16)14-7-6-12-4-2-3-5-13(12)10-14/h2-7,10,15-16,18H,8-9,11H2,1H3/t15-,16?/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake by Serotonin transporter of rat midbrain or parietal synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50086344 (4-Naphthalen-2-yl-piperidine-3-carboxylic acid met...) Show SMILES COC(=O)C1CNCC[C@H]1c1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c1-20-17(19)16-11-18-9-8-15(16)14-7-6-12-4-2-3-5-13(12)10-14/h2-7,10,15-16,18H,8-9,11H2,1H3/t15-,16?/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake by Norepinephrine transporter of rat occipital cortex synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50086344 (4-Naphthalen-2-yl-piperidine-3-carboxylic acid met...) Show SMILES COC(=O)C1CNCC[C@H]1c1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c1-20-17(19)16-11-18-9-8-15(16)14-7-6-12-4-2-3-5-13(12)10-14/h2-7,10,15-16,18H,8-9,11H2,1H3/t15-,16?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake by dopamine transporter of rat striata synaptosomes				J Med Chem 43: 1215-22 (2000) BindingDB Entry DOI: 10.7270/Q2BP03HK
					More data for this Ligand-Target Pair