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BDBM50088474 1-[2-(6-Methyl-pyridin-2-yl)-quinazolin-4-yl]-3-phenyl-urea::CHEMBL70948

SMILES: Cc1cccc(n1)-c1nc(NC(=O)Nc2ccccc2)c2ccccc2n1

InChI Key: InChIKey=ILCMOPARMHMJJY-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50088474   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))		BDBM50088474
PNG
(1-[2-(6-Methyl-pyridin-2-yl)-quinazolin-4-yl]-3-ph...)
Show SMILES Cc1cccc(n1)-c1nc(NC(=O)Nc2ccccc2)c2ccccc2n1
Show InChI InChI=1S/C21H17N5O/c1-14-8-7-13-18(22-14)20-24-17-12-6-5-11-16(17)19(25-20)26-21(27)23-15-9-3-2-4-10-15/h2-13H,1H3,(H2,23,24,25,26,27)
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PubMed
 2.64E+5n/an/an/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined by its ability to displace [125I]-AB-MECA from human adenosine A3 receptor expressed in HEK 293 cells

J Med Chem 43: 2227-38 (2000)


BindingDB Entry DOI: 10.7270/Q2T72GNJ
More data for this
Ligand-Target Pair