BDBM50088517 CHEBI:16704::URIDINE::Uridine
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
InChI Key: InChIKey=DRTQHJPVMGBUCF-XVFCMESISA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Solute carrier family 28 member 3 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human CNT3 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 5 mins by sci... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 1 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human ENT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Equilibrative nucleoside transporter 2 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.42E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human ENT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein cereblon (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | 3.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein cereblon (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | n/a | n/a | 7.57E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Equilibrative Nucleoside Transporter 1 (ENT1) (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human ENT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Equilibrative nucleoside transporter 2 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human ENT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 2 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 28 member 3 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human CNT3 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 5 mins by sci... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/nucleoside cotransporter 1 (Homo sapiens (Human)) | BDBM50088517 (CHEBI:16704 | URIDINE | Uridine) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Gilead Sciences, Inc. Curated by ChEMBL | Assay Description Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by sc... | Drug Metab Dispos 41: 916-22 (2013) Article DOI: 10.1124/dmd.112.049858 BindingDB Entry DOI: 10.7270/Q21N82VJ | |||||||||||
More data for this Ligand-Target Pair |