BDBM50088544 CHEMBL3577021

SMILES: CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)C(N)=O

InChI Key: InChIKey=OFSVTWDVZRNYRW-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50088544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50088544 (CHEMBL3577021) Show SMILES CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)C(N)=O Show InChI InChI=1S/C23H21F3N4O/c1-29-11-12-30(18-8-6-17(7-9-18)23(24,25)26)21-10-5-15(13-16(21)14-29)19-3-2-4-20(28-19)22(27)31/h2-10,13H,11-12,14H2,1H3,(H2,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Inhibition of Nav1.7 (unknown origin) by electrophysiological assay				Bioorg Med Chem Lett 25: 48-52 (2014) Article DOI: 10.1016/j.bmcl.2014.11.023 BindingDB Entry DOI: 10.7270/Q2862J67
					More data for this Ligand-Target Pair
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50088544 (CHEMBL3577021) Show SMILES CN1CCN(c2ccc(cc2)C(F)(F)F)c2ccc(cc2C1)-c1cccc(n1)C(N)=O Show InChI InChI=1S/C23H21F3N4O/c1-29-11-12-30(18-8-6-17(7-9-18)23(24,25)26)21-10-5-15(13-16(21)14-29)19-3-2-4-20(28-19)22(27)31/h2-10,13H,11-12,14H2,1H3,(H2,27,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Inhibition of Nav1.7 (unknown origin) expressed in CHO cells after 45 mins by FLIPR assay				Bioorg Med Chem Lett 25: 48-52 (2014) Article DOI: 10.1016/j.bmcl.2014.11.023 BindingDB Entry DOI: 10.7270/Q2862J67
					More data for this Ligand-Target Pair