BDBM50089138 CHEMBL3577714

SMILES: COCC#Cc1cc(O[C@@H](C)COC)cc(c1)C(=O)Nc1ccn(C)n1

InChI Key: InChIKey=DKVKMRIPGMRAQU-AWEZNQCLSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50089138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucokinase/Glucokinase regulatory protein (Homo sapiens (Human))	BDBM50089138 (CHEMBL3577714) Show SMILES COCC#Cc1cc(O[C@@H](C)COC)cc(c1)C(=O)Nc1ccn(C)n1 |r| Show InChI InChI=1S/C19H23N3O4/c1-14(13-25-4)26-17-11-15(6-5-9-24-3)10-16(12-17)19(23)20-18-7-8-22(2)21-18/h7-8,10-12,14H,9,13H2,1-4H3,(H,20,21,23)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a
Yuhan Research Institute Curated by ChEMBL					Assay Description Activation of recombinant human pancreatic glucokinase using 10 mM glucose as substrate by G6PDH coupled assay				ACS Med Chem Lett 6: 296-301 (2015) Article DOI: 10.1021/ml5004712 BindingDB Entry DOI: 10.7270/Q2ZP47VT
					More data for this Ligand-Target Pair