BDBM50089489 CHEMBL286437::N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-4-(5-naphthalen-2-ylmethyl-[1,2,4]oxadiazol-3-yl)-benzenesulfonamide

SMILES: O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2noc(Cc3ccc4ccccc4c3)n2)cc1)c1cccnc1

InChI Key: InChIKey=HCRWXYFCVVDWAC-YTTGMZPUSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50089489 (CHEMBL286437 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-...) Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2noc(Cc3ccc4ccccc4c3)n2)cc1)c1cccnc1 Show InChI InChI=1S/C34H31N5O4S/c40-32(29-6-3-18-35-22-29)23-36-19-17-24-8-13-30(14-9-24)39-44(41,42)31-15-11-27(12-16-31)34-37-33(43-38-34)21-25-7-10-26-4-1-2-5-28(26)20-25/h1-16,18,20,22,32,36,39-40H,17,19,21,23H2/t32-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to recombinant human beta-2 adrenergic receptor prepared from CHO cells in the presence of [125I]-iodocyanopindolol				Bioorg Med Chem Lett 10: 1431-4 (2000) BindingDB Entry DOI: 10.7270/Q24B30JM
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50089489 (CHEMBL286437 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-...) Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2noc(Cc3ccc4ccccc4c3)n2)cc1)c1cccnc1 Show InChI InChI=1S/C34H31N5O4S/c40-32(29-6-3-18-35-22-29)23-36-19-17-24-8-13-30(14-9-24)39-44(41,42)31-15-11-27(12-16-31)34-37-33(43-38-34)21-25-7-10-26-4-1-2-5-28(26)20-25/h1-16,18,20,22,32,36,39-40H,17,19,21,23H2/t32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Stimulation of cAMP levels in CHO cells expressing the recombinant human beta-3 adrenergic receptor				Bioorg Med Chem Lett 10: 1431-4 (2000) BindingDB Entry DOI: 10.7270/Q24B30JM
					More data for this Ligand-Target Pair
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50089489 (CHEMBL286437 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-...) Show SMILES O[C@@H](CNCCc1ccc(NS(=O)(=O)c2ccc(cc2)-c2noc(Cc3ccc4ccccc4c3)n2)cc1)c1cccnc1 Show InChI InChI=1S/C34H31N5O4S/c40-32(29-6-3-18-35-22-29)23-36-19-17-24-8-13-30(14-9-24)39-44(41,42)31-15-11-27(12-16-31)34-37-33(43-38-34)21-25-7-10-26-4-1-2-5-28(26)20-25/h1-16,18,20,22,32,36,39-40H,17,19,21,23H2/t32-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to recombinant human beta-1 adrenergic receptor expressed in CHO cells in the presence of [125I]-iodocyanopindolol				Bioorg Med Chem Lett 10: 1431-4 (2000) BindingDB Entry DOI: 10.7270/Q24B30JM
					More data for this Ligand-Target Pair