BDBM50090406 1-(5-(4,5-dihydrooxazol-2-yl)-2-(thiophen-2-yl)pyrimidin-4-ylamino)-3-methyl-1H-pyrrole-2,5-dione::1-[5-(4,5-Dihydro-oxazol-2-yl)-2-thiophen-2-yl-pyrimidin-4-ylamino]-3-methyl-pyrrole-2,5-dione::CHEMBL295508

SMILES: CC1=CC(=O)N(Nc2nc(ncc2C2=NCCO2)-c2cccs2)C1=O

InChI Key: InChIKey=PTHWPWGFLGQPPP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50090406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene c-JUN/protein c-fos (Homo sapiens (Human))	BDBM50090406 (1-(5-(4,5-dihydrooxazol-2-yl)-2-(thiophen-2-yl)pyr...) Show SMILES CC1=CC(=O)N(Nc2nc(ncc2C2=NCCO2)-c2cccs2)C1=O |t:1,14| Show InChI InChI=1S/C16H13N5O3S/c1-9-7-12(22)21(16(9)23)20-13-10(15-17-4-5-24-15)8-18-14(19-13)11-3-2-6-25-11/h2-3,6-8H,4-5H2,1H3,(H,18,19,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Signal Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells				Bioorg Med Chem Lett 10: 1645-8 (2000) BindingDB Entry DOI: 10.7270/Q2F190XH
					More data for this Ligand-Target Pair