BDBM50090491 (R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-6-one O-benzyl-oxime::CHEMBL46773

SMILES: Clc1ccc(cc1)[C@@H]1CCN2CC1\C(C2)=N\OCc1ccccc1

InChI Key: InChIKey=DFQUNPJCRZACIT-DCDOZRBTSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50090491 ((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES Clc1ccc(cc1)[C@@H]1CCN2CC1\C(C2)=N\OCc1ccccc1 |TLB:15:13:11:7.8.9,THB:4:7:11:13.14| Show InChI InChI=1S/C20H21ClN2O/c21-17-8-6-16(7-9-17)18-10-11-23-12-19(18)20(13-23)22-24-14-15-4-2-1-3-5-15/h1-9,18-19H,10-14H2/b22-20+/t18-,19?/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090491 ((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES Clc1ccc(cc1)[C@@H]1CCN2CC1\C(C2)=N\OCc1ccccc1 |TLB:15:13:11:7.8.9,THB:4:7:11:13.14| Show InChI InChI=1S/C20H21ClN2O/c21-17-8-6-16(7-9-17)18-10-11-23-12-19(18)20(13-23)22-24-14-15-4-2-1-3-5-15/h1-9,18-19H,10-14H2/b22-20+/t18-,19?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50090491 ((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES Clc1ccc(cc1)[C@@H]1CCN2CC1\C(C2)=N\OCc1ccccc1 |TLB:15:13:11:7.8.9,THB:4:7:11:13.14| Show InChI InChI=1S/C20H21ClN2O/c21-17-8-6-16(7-9-17)18-10-11-23-12-19(18)20(13-23)22-24-14-15-4-2-1-3-5-15/h1-9,18-19H,10-14H2/b22-20+/t18-,19?/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090491 ((R)-4-(4-Chloro-phenyl)-1-aza-bicyclo[3.2.1]octan-...) Show SMILES Clc1ccc(cc1)[C@@H]1CCN2CC1\C(C2)=N\OCc1ccccc1 |TLB:15:13:11:7.8.9,THB:4:7:11:13.14| Show InChI InChI=1S/C20H21ClN2O/c21-17-8-6-16(7-9-17)18-10-11-23-12-19(18)20(13-23)22-24-14-15-4-2-1-3-5-15/h1-9,18-19H,10-14H2/b22-20+/t18-,19?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]- Mazindol binding to dopamine transporter of rat striatal membrane.				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair