BDBM50090500 4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid 3-phenyl-propyl ester::CHEMBL47068

SMILES: CN1CCC(C(C1)C(=O)OCCCc1ccccc1)c1ccc(Cl)cc1

InChI Key: InChIKey=PKDKAGWKUOJCLX-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Norepinephrine Monoamine transporters (Rattus norvegicus)	BDBM50090500 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CN1CCC(C(C1)C(=O)OCCCc1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClNO2/c1-24-14-13-20(18-9-11-19(23)12-10-18)21(16-24)22(25)26-15-5-8-17-6-3-2-4-7-17/h2-4,6-7,9-12,20-21H,5,8,13-16H2,1H3	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090500 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CN1CCC(C(C1)C(=O)OCCCc1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClNO2/c1-24-14-13-20(18-9-11-19(23)12-10-18)21(16-24)22(25)26-15-5-8-17-6-3-2-4-7-17/h2-4,6-7,9-12,20-21H,5,8,13-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA binding to dopamine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50090500 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CN1CCC(C(C1)C(=O)OCCCc1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClNO2/c1-24-14-13-20(18-9-11-19(23)12-10-18)21(16-24)22(25)26-15-5-8-17-6-3-2-4-7-17/h2-4,6-7,9-12,20-21H,5,8,13-16H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE binding to norepinephrine transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50090500 (4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxyl...) Show SMILES CN1CCC(C(C1)C(=O)OCCCc1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H26ClNO2/c1-24-14-13-20(18-9-11-19(23)12-10-18)21(16-24)22(25)26-15-5-8-17-6-3-2-4-7-17/h2-4,6-7,9-12,20-21H,5,8,13-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]-5-HT binding to serotonin transporter of rat brain synaptosomes				Bioorg Med Chem Lett 10: 1681-6 (2000) BindingDB Entry DOI: 10.7270/Q2MG7Q0C
					More data for this Ligand-Target Pair