BDBM50092555 4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrimidin-5-yl-piperazin-1-yl)-ethyl ester::CHEMBL125926

SMILES: COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1cncnc1

InChI Key: InChIKey=LXEWDHGRBMSERP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50092555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (5-HT4) (Homo sapiens (Human))	BDBM50092555 (4-Amino-5-chloro-2-methoxy-benzoic acid 2-(4-pyrim...) Show SMILES COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(CC1)c1cncnc1 Show InChI InChI=1S/C18H22ClN5O3/c1-26-17-9-16(20)15(19)8-14(17)18(25)27-7-6-23-2-4-24(5-3-23)13-10-21-12-22-11-13/h8-12H,2-7,20H2,1H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4E receptor isoform expressed in C6 glial cells incubated with 0.2 nM [3H]-GR-113,...				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair