BDBM50092976 CHEMBL3586478
SMILES: CSCC[C@H](NC(=O)Cc1cccs1)C(=O)SCC(O)=O
InChI Key: InChIKey=NZHCYWWTEYUPNE-JTQLQIEISA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase L1 (Stenotrophomonas maltophilia) | BDBM50092976 (CHEMBL3586478) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Mixed-type inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mi... | ACS Med Chem Lett 6: 660-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00098 BindingDB Entry DOI: 10.7270/Q2M04769 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase type II (Bacteroides fragilis) | BDBM50092976 (CHEMBL3586478) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of Bacteroides fragilis CcrA overexpressed in Escherichia coli BL21 (DE3) using cefazolin as substrate incubated for 30 mins prior to test... | ACS Med Chem Lett 6: 660-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00098 BindingDB Entry DOI: 10.7270/Q2M04769 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-lactamase L1 (Stenotrophomonas maltophilia) | BDBM50092976 (CHEMBL3586478) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Northwest University Curated by ChEMBL | Assay Description Inhibition of Stenotrophomonas maltophilia L1 overexpressed in Escherichia coli BL21 (DE3) using imipenem as substrate incubated for 30 mins prior to... | ACS Med Chem Lett 6: 660-4 (2015) Article DOI: 10.1021/acsmedchemlett.5b00098 BindingDB Entry DOI: 10.7270/Q2M04769 | |||||||||||
More data for this Ligand-Target Pair |