BDBM50093305 2-(4-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1-yl)-pentyl]-4H-benzo[1,4]oxazin-3-one::CHEMBL423160

SMILES: CC1CCCC(C)N1CCCCCN1C(=O)C(Oc2ccccc12)c1ccc(Cl)cc1

InChI Key: InChIKey=LKWOZWCLKKPBJR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50093305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50093305 (2-(4-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1...) Show SMILES CC1CCCC(C)N1CCCCCN1C(=O)C(Oc2ccccc12)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H33ClN2O2/c1-19-9-8-10-20(2)28(19)17-6-3-7-18-29-23-11-4-5-12-24(23)31-25(26(29)30)21-13-15-22(27)16-14-21/h4-5,11-16,19-20,25H,3,6-10,17-18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description In vitro inhibition of coagulation factor Xa.				J Med Chem 43: 4063-70 (2000) BindingDB Entry DOI: 10.7270/Q2W66K1H
					More data for this Ligand-Target Pair