BDBM50095339 3,5,7-Trihydroxy-2-(4-iodo-phenyl)-chromen-4-one::CHEMBL166368

SMILES: Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(I)cc1

InChI Key: InChIKey=JZGNQOUGTXYCBJ-UHFFFAOYSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P-glycoprotein 1 (Homo sapiens (Human))	BDBM50095339 (3,5,7-Trihydroxy-2-(4-iodo-phenyl)-chromen-4-one |...) Show SMILES Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(I)cc1 Show InChI InChI=1S/C15H9IO5/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,17-18,20H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
Chosun University Curated by ChEMBL					Assay Description Binding affinity to ABCB1 nucleotide binding domain 2				Eur J Med Chem 46: 4078-88 (2011) Article DOI: 10.1016/j.ejmech.2011.06.008 BindingDB Entry DOI: 10.7270/Q2FJ2J3W
					More data for this Ligand-Target Pair
P-glycoprotein (P-gp) (Mus musculus (Mouse))	BDBM50095339 (3,5,7-Trihydroxy-2-(4-iodo-phenyl)-chromen-4-one |...) Show SMILES Oc1cc(O)c2c(c1)oc(c(O)c2=O)-c1ccc(I)cc1 Show InChI InChI=1S/C15H9IO5/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,17-18,20H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a
Département de Pharmacochimie Moléculaire UMR-CNRS 5063 Curated by ChEMBL					Assay Description Binding affinity of the compound to nucleotide-binding domain (NBD2) of P-Glycoprotein				Bioorg Med Chem Lett 11: 75-7 (2001) BindingDB Entry DOI: 10.7270/Q2T43SC1
					More data for this Ligand-Target Pair