BDBM50096381 4-Methanesulfonyl-N-[(S)-3-methyl-1-(4-oxo-tetrahydro-furan-3-ylcarbamoyl)-butyl]-benzamide::CHEMBL59738

SMILES: CC(C)C[C@H](NC(=O)c1ccc(cc1)S(C)(=O)=O)C(=O)NC1COCC1=O

InChI Key: InChIKey=HXMTXUKKTYGOEU-MLCCFXAWSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50096381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50096381 (4-Methanesulfonyl-N-[(S)-3-methyl-1-(4-oxo-tetrahy...) Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1)S(C)(=O)=O)C(=O)NC1COCC1=O Show InChI InChI=1S/C18H24N2O6S/c1-11(2)8-14(18(23)20-15-9-26-10-16(15)21)19-17(22)12-4-6-13(7-5-12)27(3,24)25/h4-7,11,14-15H,8-10H2,1-3H3,(H,19,22)(H,20,23)/t14-,15?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against human cysteine protease, cathepsin K.				Bioorg Med Chem Lett 11: 195-8 (2001) BindingDB Entry DOI: 10.7270/Q2ZP45CQ
					More data for this Ligand-Target Pair