null

SMILES: CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(O)=O)C(=O)Nc1ccncc1

InChI Key: InChIKey=GBABKPSGHJLCTJ-WIYYLYMNSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50097234 ((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(O)=O)C(=O)Nc1ccncc1 Show InChI InChI=1S/C24H31N3O4/c1-24(2,3)21(23(31)26-19-12-14-25-15-13-19)27-22(30)18(16-20(28)29)11-7-10-17-8-5-4-6-9-17/h4-6,8-9,12-15,18,21H,7,10-11,16H2,1-3H3,(H,27,30)(H,28,29)(H,25,26,31)/t18-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.				Bioorg Med Chem Lett 11: 567-70 (2001) BindingDB Entry DOI: 10.7270/Q2610ZK1
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50097234 ((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(O)=O)C(=O)Nc1ccncc1 Show InChI InChI=1S/C24H31N3O4/c1-24(2,3)21(23(31)26-19-12-14-25-15-13-19)27-22(30)18(16-20(28)29)11-7-10-17-8-5-4-6-9-17/h4-6,8-9,12-15,18,21H,7,10-11,16H2,1-3H3,(H,27,30)(H,28,29)(H,25,26,31)/t18-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50097234 ((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(O)=O)C(=O)Nc1ccncc1 Show InChI InChI=1S/C24H31N3O4/c1-24(2,3)21(23(31)26-19-12-14-25-15-13-19)27-22(30)18(16-20(28)29)11-7-10-17-8-5-4-6-9-17/h4-6,8-9,12-15,18,21H,7,10-11,16H2,1-3H3,(H,27,30)(H,28,29)(H,25,26,31)/t18-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	275	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50097234 ((R)-3-(((S)-3,3-dimethyl-1-oxo-1-(pyridin-4-ylamin...) Show SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(O)=O)C(=O)Nc1ccncc1 Show InChI InChI=1S/C24H31N3O4/c1-24(2,3)21(23(31)26-19-12-14-25-15-13-19)27-22(30)18(16-20(28)29)11-7-10-17-8-5-4-6-9-17/h4-6,8-9,12-15,18,21H,7,10-11,16H2,1-3H3,(H,27,30)(H,28,29)(H,25,26,31)/t18-,21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.				Bioorg Med Chem Lett 11: 567-70 (2001) BindingDB Entry DOI: 10.7270/Q2610ZK1
					More data for this Ligand-Target Pair