BDBM50097423 4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide::4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benzamide(LUF5417)::4-methoxy-N-(3-phenyl-1,2,4-thiadiazol-5-yl)benzamide::CHEMBL305322::LUF-5417
SMILES: COc1ccc(cc1)C(=O)Nc1nc(ns1)-c1ccccc1
InChI Key: InChIKey=RGVXOHBJCGPTQH-UHFFFAOYSA-N
Data: 8 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL | Assay Description Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat cortical membrane | Bioorg Med Chem Lett 11: 2017-9 (2001) BindingDB Entry DOI: 10.7270/Q2HM57QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain cortical membrane in presence of 100 uM GTP | Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Curated by ChEMBL | Assay Description Displacement of [3H]DPCPX binding to adenosine A1 receptor of rat brain cortical membrane | J Med Chem 44: 749-62 (2001) BindingDB Entry DOI: 10.7270/Q2H132Q0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL | Assay Description Displacement of [125I]-AB MECA from human Adenosine A3 receptor expressed in HEK 293 cells | Bioorg Med Chem Lett 11: 2017-9 (2001) BindingDB Entry DOI: 10.7270/Q2HM57QP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Curated by ChEMBL | Assay Description Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cells | J Med Chem 44: 749-62 (2001) BindingDB Entry DOI: 10.7270/Q2H132Q0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 82 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Binding affinity to human adenosine A3 receptor | Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vrije Universiteit Curated by ChEMBL | Assay Description Displacement of [3H]-CGS-21,680 or [3H]ZM-241385 binding in adenosine A2A receptor of rat striatal membrane was determined | J Med Chem 44: 749-62 (2001) BindingDB Entry DOI: 10.7270/Q2H132Q0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat)) | BDBM50097423 (4-Methoxy-N-(3-phenyl-[1,2,4]thiadiazol-5-yl)-benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatum membrane | Bioorg Med Chem 18: 2195-203 (2010) Article DOI: 10.1016/j.bmc.2010.01.072 BindingDB Entry DOI: 10.7270/Q2BZ670J | |||||||||||
More data for this Ligand-Target Pair |