BDBM50097594 3-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin-3-yl]-quinoline::CHEMBL157135

SMILES: CN1CCC[C@H]1COc1cncc(c1)-c1cnc2ccccc2c1

InChI Key: InChIKey=JECPNJSOZLQZFX-SFHVURJKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097594   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50097594 (3-[5-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-pyridin...) Show SMILES CN1CCC[C@H]1COc1cncc(c1)-c1cnc2ccccc2c1 Show InChI InChI=1S/C20H21N3O/c1-23-8-4-6-18(23)14-24-19-10-17(11-21-13-19)16-9-15-5-2-3-7-20(15)22-12-16/h2-3,5,7,9-13,18H,4,6,8,14H2,1H3/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro ability to displace [3H]-(-)-cytisine binding to whole rat brain membranes at Nicotinic acetylcholine receptor alpha4-beta2				Bioorg Med Chem Lett 11: 631-3 (2001) BindingDB Entry DOI: 10.7270/Q2WM1CPS
					More data for this Ligand-Target Pair