BDBM50097984 5-(4-Methoxy-phenyl)-7-pyrrolidin-3-yl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::CHEMBL352652

SMILES: COc1ccc(cc1)-c1cn(C2CCNC2)c2ncnc(N)c12

InChI Key: InChIKey=WDYVDTYEQJWMHJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50097984 (5-(4-Methoxy-phenyl)-7-pyrrolidin-3-yl-7H-pyrrolo[...) Show SMILES COc1ccc(cc1)-c1cn(C2CCNC2)c2ncnc(N)c12 Show InChI InChI=1S/C17H19N5O/c1-23-13-4-2-11(3-5-13)14-9-22(12-6-7-19-8-12)17-15(14)16(18)20-10-21-17/h2-5,9-10,12,19H,6-8H2,1H3,(H2,18,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mL				Bioorg Med Chem Lett 11: 853-6 (2001) BindingDB Entry DOI: 10.7270/Q29P30XJ
					More data for this Ligand-Target Pair