BDBM50097988 (R)-4-[(R)-4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-2-ethoxycarbonylmethyl-pyrrolidine-1-carboxylic acid tert-butyl ester::CHEMBL352666

SMILES: CCOC(=O)C[C@H]1C[C@@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12

InChI Key: InChIKey=QQIZZZZYZWSQLD-SJORKVTESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50097988 ((R)-4-[(R)-4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,...) Show SMILES CCOC(=O)C[C@H]1C[C@@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 Show InChI InChI=1S/C25H31N5O5/c1-5-34-20(32)11-16-10-17(12-30(16)24(33)35-25(2,3)4)29-13-19(15-6-8-18(31)9-7-15)21-22(26)27-14-28-23(21)29/h6-9,13-14,16-17,31H,5,10-12H2,1-4H3,(H2,26,27,28)/t16-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mL				Bioorg Med Chem Lett 11: 853-6 (2001) BindingDB Entry DOI: 10.7270/Q29P30XJ
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Gallus gallus (Chicken))	BDBM50097988 ((R)-4-[(R)-4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,...) Show SMILES CCOC(=O)C[C@H]1C[C@@H](CN1C(=O)OC(C)(C)C)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12 Show InChI InChI=1S/C25H31N5O5/c1-5-34-20(32)11-16-10-17(12-30(16)24(33)35-25(2,3)4)29-13-19(15-6-8-18(31)9-7-15)21-22(26)27-14-28-23(21)29/h6-9,13-14,16-17,31H,5,10-12H2,1-4H3,(H2,26,27,28)/t16-,17+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Research Curated by ChEMBL					Assay Description Concentration required for inhibition of c-Src mediated phosphorylation of Fak in IC8.1 fibroblast cell assay				Bioorg Med Chem Lett 11: 853-6 (2001) BindingDB Entry DOI: 10.7270/Q29P30XJ
					More data for this Ligand-Target Pair