BDBM50098644 2,7-Dichloro-9H-xanthene-9-carboxylic acid (1-cyclooct-1-enylmethyl-piperidin-4-yl)-amide::CHEMBL33639
SMILES: Clc1ccc2Oc3ccc(Cl)cc3C(C(=O)NC3CCN(C\C4=C\CCCCCC4)CC3)c2c1
InChI Key: InChIKey=YWCUXSPKJLKOPM-KPSZGOFPSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-C chemokine receptor type 1 (Homo sapiens (Human)) | BDBM50098644 (2,7-Dichloro-9H-xanthene-9-carboxylic acid (1-cycl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibitory activity against [125I]-MIP-1 alpha binding to human CCR1 receptors. | J Med Chem 44: 1429-35 (2001) BindingDB Entry DOI: 10.7270/Q2G73D0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-C chemokine receptor type 1 (Mus musculus) | BDBM50098644 (2,7-Dichloro-9H-xanthene-9-carboxylic acid (1-cycl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibitory activity against [125I]-MIP-1 alpha binding to mouse CCR1 receptors. | J Med Chem 44: 1429-35 (2001) BindingDB Entry DOI: 10.7270/Q2G73D0G | |||||||||||
More data for this Ligand-Target Pair |