BDBM50098999 5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,3']bipyridinyl-6'-carboxylic acid::CHEMBL268470
SMILES: CS(=O)(=O)c1ccc(cc1)-c1cc(Cl)cnc1-c1ccc(nc1)C(O)=O
InChI Key: InChIKey=QIHJKHCGJLIAGS-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclooxygenase (Homo sapiens (Human)) | BDBM50098999 (5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,3']bipyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description In vitro inhibition of Prostaglandin G/H synthase 2 in human whole blood assay | Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human)) | BDBM50098999 (5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,3']bipyri...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description In vitro inhibition of Prostaglandin G/H synthase 1 in human whole blood assay | Bioorg Med Chem Lett 11: 1059-62 (2001) BindingDB Entry DOI: 10.7270/Q25Q4VC6 | |||||||||||
More data for this Ligand-Target Pair |