BDBM50099150 CHEMBL368584::N-[5-(2-{1-[4-((R)-3,5-Dioxo-[1,2,4]oxadiazolidin-2-ylmethyl)-phenyl]-piperidin-4-ylamino}-1-hydroxy-ethyl)-2-hydroxy-phenyl]-methanesulfonamide

SMILES: CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CNC1CCN(CC1)c1ccc(Cn2oc(=O)[nH]c2=O)cc1

InChI Key: InChIKey=ZUOQKJZGQFTKGQ-NRFANRHFSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-1 adrenergic receptor (Homo sapiens (Human))	BDBM50099150 (CHEMBL368584 | N-[5-(2-{1-[4-((R)-3,5-Dioxo-[1,2,4...) Show SMILES CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CNC1CCN(CC1)c1ccc(Cn2oc(=O)[nH]c2=O)cc1 Show InChI InChI=1S/C23H29N5O7S/c1-36(33,34)26-19-12-16(4-7-20(19)29)21(30)13-24-17-8-10-27(11-9-17)18-5-2-15(3-6-18)14-28-22(31)25-23(32)35-28/h2-7,12,17,21,24,26,29-30H,8-11,13-14H2,1H3,(H,25,31,32)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	9.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of 125 I-Iodocyanopindolol binding to Beta-1 adrenergic receptor				Bioorg Med Chem Lett 11: 981-4 (2001) BindingDB Entry DOI: 10.7270/Q2125RZ5
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM50099150 (CHEMBL368584 | N-[5-(2-{1-[4-((R)-3,5-Dioxo-[1,2,4...) Show SMILES CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CNC1CCN(CC1)c1ccc(Cn2oc(=O)[nH]c2=O)cc1 Show InChI InChI=1S/C23H29N5O7S/c1-36(33,34)26-19-12-16(4-7-20(19)29)21(30)13-24-17-8-10-27(11-9-17)18-5-2-15(3-6-18)14-28-22(31)25-23(32)35-28/h2-7,12,17,21,24,26,29-30H,8-11,13-14H2,1H3,(H,25,31,32)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibition of 125 I-Iodocyanopindolol binding to Beta-2 adrenergic receptor				Bioorg Med Chem Lett 11: 981-4 (2001) BindingDB Entry DOI: 10.7270/Q2125RZ5
					More data for this Ligand-Target Pair
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50099150 (CHEMBL368584 | N-[5-(2-{1-[4-((R)-3,5-Dioxo-[1,2,4...) Show SMILES CS(=O)(=O)Nc1cc(ccc1O)[C@@H](O)CNC1CCN(CC1)c1ccc(Cn2oc(=O)[nH]c2=O)cc1 Show InChI InChI=1S/C23H29N5O7S/c1-36(33,34)26-19-12-16(4-7-20(19)29)21(30)13-24-17-8-10-27(11-9-17)18-5-2-15(3-6-18)14-28-22(31)25-23(32)35-28/h2-7,12,17,21,24,26,29-30H,8-11,13-14H2,1H3,(H,25,31,32)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Beta 3-adrenergic receptor agonistic activity, evaluated by measurement of cAMP accumulation in CHO cells.				Bioorg Med Chem Lett 11: 981-4 (2001) BindingDB Entry DOI: 10.7270/Q2125RZ5
					More data for this Ligand-Target Pair