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SMILES: CN1C[C@H]([C@@H](C1)c1ccccc1)C(=O)c1ccccn1

InChI Key: InChIKey=ZYZPGKZYHIMRSG-LSDHHAIUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50099313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transporter (Rattus norvegicus)	BDBM50099313 (((3S,4R)-1-Methyl-4-phenyl-pyrrolidin-3-yl)-pyridi...) Show SMILES CN1C[C@H]([C@@H](C1)c1ccccc1)C(=O)c1ccccn1 Show InChI InChI=1S/C17H18N2O/c1-19-11-14(13-7-3-2-4-8-13)15(12-19)17(20)16-9-5-6-10-18-16/h2-10,14-15H,11-12H2,1H3/t14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]NE uptake at Norepinephrine transporter in rat parietal/occipital cortex was determined				Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099313 (((3S,4R)-1-Methyl-4-phenyl-pyrrolidin-3-yl)-pyridi...) Show SMILES CN1C[C@H]([C@@H](C1)c1ccccc1)C(=O)c1ccccn1 Show InChI InChI=1S/C17H18N2O/c1-19-11-14(13-7-3-2-4-8-13)15(12-19)17(20)16-9-5-6-10-18-16/h2-10,14-15H,11-12H2,1H3/t14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.				Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50099313 (((3S,4R)-1-Methyl-4-phenyl-pyrrolidin-3-yl)-pyridi...) Show SMILES CN1C[C@H]([C@@H](C1)c1ccccc1)C(=O)c1ccccn1 Show InChI InChI=1S/C17H18N2O/c1-19-11-14(13-7-3-2-4-8-13)15(12-19)17(20)16-9-5-6-10-18-16/h2-10,14-15H,11-12H2,1H3/t14-,15+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	830	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT uptake at Serotonin transporter in rat mid brain				Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099313 (((3S,4R)-1-Methyl-4-phenyl-pyrrolidin-3-yl)-pyridi...) Show SMILES CN1C[C@H]([C@@H](C1)c1ccccc1)C(=O)c1ccccn1 Show InChI InChI=1S/C17H18N2O/c1-19-11-14(13-7-3-2-4-8-13)15(12-19)17(20)16-9-5-6-10-18-16/h2-10,14-15H,11-12H2,1H3/t14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	645	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Inhibition of [3H]DA uptake at Dopamine transporter in rat cortex.				Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099313 (((3S,4R)-1-Methyl-4-phenyl-pyrrolidin-3-yl)-pyridi...) Show SMILES CN1C[C@H]([C@@H](C1)c1ccccc1)C(=O)c1ccccn1 Show InChI InChI=1S/C17H18N2O/c1-19-11-14(13-7-3-2-4-8-13)15(12-19)17(20)16-9-5-6-10-18-16/h2-10,14-15H,11-12H2,1H3/t14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	494	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Functional cocaine antagonism was evaluated by inhibition of [3H]dopamine reuptake at a concentration of 300 nM with cocaine				Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50099313 (((3S,4R)-1-Methyl-4-phenyl-pyrrolidin-3-yl)-pyridi...) Show SMILES CN1C[C@H]([C@@H](C1)c1ccccc1)C(=O)c1ccccn1 Show InChI InChI=1S/C17H18N2O/c1-19-11-14(13-7-3-2-4-8-13)15(12-19)17(20)16-9-5-6-10-18-16/h2-10,14-15H,11-12H2,1H3/t14-,15+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	663	n/a	n/a	n/a	n/a	n/a	n/a
Georgetown University Medical Center Curated by ChEMBL					Assay Description Functional cocaine antagonism was evaluated by inhibition of [3H]dopamine reuptake				Bioorg Med Chem Lett 11: 1113-8 (2001) BindingDB Entry DOI: 10.7270/Q24M952F
					More data for this Ligand-Target Pair