BDBM50101329 CHEMBL3326391
SMILES: [H][C@@]12C[C@]1(N)CC[C@@H]2C(O)=O
InChI Key: InChIKey=YFGNHEYEOLSERH-KZLJYQGOSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GABA transporter 3 (Homo sapiens (Human)) | BDBM50101329![]() (CHEMBL3326391) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.63E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of human GAT3 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | ACS Med Chem Lett 5: 889-93 (2014) Article DOI: 10.1021/ml500134k BindingDB Entry DOI: 10.7270/Q2WH2RS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Betaine transporter (Homo sapiens (Human)) | BDBM50101329![]() (CHEMBL3326391) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of human BGT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | ACS Med Chem Lett 5: 889-93 (2014) Article DOI: 10.1021/ml500134k BindingDB Entry DOI: 10.7270/Q2WH2RS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA transporter 1 (Homo sapiens (Human)) | BDBM50101329![]() (CHEMBL3326391) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of human GAT1 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | ACS Med Chem Lett 5: 889-93 (2014) Article DOI: 10.1021/ml500134k BindingDB Entry DOI: 10.7270/Q2WH2RS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA transporter 2 (Homo sapiens (Human)) | BDBM50101329![]() (CHEMBL3326391) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido University Curated by ChEMBL | Assay Description Inhibition of human GAT2 transfected in CHO cells assessed as [3H]GABA uptake after 20 mins by liquid scintillation counting analysis | ACS Med Chem Lett 5: 889-93 (2014) Article DOI: 10.1021/ml500134k BindingDB Entry DOI: 10.7270/Q2WH2RS1 | |||||||||||
More data for this Ligand-Target Pair |