null

SMILES: OC(CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O)c1ccccc1

InChI Key: InChIKey=DCVWTZSLJPJYFB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50102334 (3-(4-(4-nitrophenyl)piperazin-1-yl)-1-phenylpropan...) Show SMILES OC(CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O)c1ccccc1 Show InChI InChI=1S/C19H23N3O3/c23-19(16-4-2-1-3-5-16)10-11-20-12-14-21(15-13-20)17-6-8-18(9-7-17)22(24)25/h1-9,19,23H,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetine				J Med Chem 44: 418-28 (2001) BindingDB Entry DOI: 10.7270/Q22B8XBC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50102334 (3-(4-(4-nitrophenyl)piperazin-1-yl)-1-phenylpropan...) Show SMILES OC(CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O)c1ccccc1 Show InChI InChI=1S/C19H23N3O3/c23-19(16-4-2-1-3-5-16)10-11-20-12-14-21(15-13-20)17-6-8-18(9-7-17)22(24)25/h1-9,19,23H,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligand				J Med Chem 44: 418-28 (2001) BindingDB Entry DOI: 10.7270/Q22B8XBC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50102334 (3-(4-(4-nitrophenyl)piperazin-1-yl)-1-phenylpropan...) Show SMILES OC(CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O)c1ccccc1 Show InChI InChI=1S/C19H23N3O3/c23-19(16-4-2-1-3-5-16)10-11-20-12-14-21(15-13-20)17-6-8-18(9-7-17)22(24)25/h1-9,19,23H,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor				Eur J Med Chem 43: 364-72 (2008) Article DOI: 10.1016/j.ejmech.2007.03.036 BindingDB Entry DOI: 10.7270/Q2SQ91NB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50102334 (3-(4-(4-nitrophenyl)piperazin-1-yl)-1-phenylpropan...) Show SMILES OC(CCN1CCN(CC1)c1ccc(cc1)[N+]([O-])=O)c1ccccc1 Show InChI InChI=1S/C19H23N3O3/c23-19(16-4-2-1-3-5-16)10-11-20-12-14-21(15-13-20)17-6-8-18(9-7-17)22(24)25/h1-9,19,23H,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal da Para£ba Curated by ChEMBL					Assay Description Antagonist activity at 5HT1A				Eur J Med Chem 45: 1508-14 (2010) Article DOI: 10.1016/j.ejmech.2009.12.059 BindingDB Entry DOI: 10.7270/Q2HX1DX1
					More data for this Ligand-Target Pair