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SMILES: FC(F)(F)c1ccc(OC(CCN2CCN(CC2)c2ccccn2)c2ccccc2)cc1

InChI Key: InChIKey=BFUZKYZYAVZLHQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50102368 (1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)-...) Show SMILES FC(F)(F)c1ccc(OC(CCN2CCN(CC2)c2ccccn2)c2ccccc2)cc1 Show InChI InChI=1S/C25H26F3N3O/c26-25(27,28)21-9-11-22(12-10-21)32-23(20-6-2-1-3-7-20)13-15-30-16-18-31(19-17-30)24-8-4-5-14-29-24/h1-12,14,23H,13,15-19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Binding affinity towards Serotonin transporter from rat cortex measured using [3H]-paroxetine				J Med Chem 44: 418-28 (2001) BindingDB Entry DOI: 10.7270/Q22B8XBC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50102368 (1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)-...) Show SMILES FC(F)(F)c1ccc(OC(CCN2CCN(CC2)c2ccccn2)c2ccccc2)cc1 Show InChI InChI=1S/C25H26F3N3O/c26-25(27,28)21-9-11-22(12-10-21)32-23(20-6-2-1-3-7-20)13-15-30-16-18-31(19-17-30)24-8-4-5-14-29-24/h1-12,14,23H,13,15-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal da Para£ba Curated by ChEMBL					Assay Description Antagonist activity at 5HT1A				Eur J Med Chem 45: 1508-14 (2010) Article DOI: 10.1016/j.ejmech.2009.12.059 BindingDB Entry DOI: 10.7270/Q2HX1DX1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50102368 (1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)-...) Show SMILES FC(F)(F)c1ccc(OC(CCN2CCN(CC2)c2ccccn2)c2ccccc2)cc1 Show InChI InChI=1S/C25H26F3N3O/c26-25(27,28)21-9-11-22(12-10-21)32-23(20-6-2-1-3-7-20)13-15-30-16-18-31(19-17-30)24-8-4-5-14-29-24/h1-12,14,23H,13,15-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Binding affinity to 5HT1A receptor				Eur J Med Chem 43: 364-72 (2008) Article DOI: 10.1016/j.ejmech.2007.03.036 BindingDB Entry DOI: 10.7270/Q2SQ91NB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50102368 (1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)-...) Show SMILES FC(F)(F)c1ccc(OC(CCN2CCN(CC2)c2ccccn2)c2ccccc2)cc1 Show InChI InChI=1S/C25H26F3N3O/c26-25(27,28)21-9-11-22(12-10-21)32-23(20-6-2-1-3-7-20)13-15-30-16-18-31(19-17-30)24-8-4-5-14-29-24/h1-12,14,23H,13,15-19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor (5-HT 1A receptor, serotonin receptor) from rat cortex using [3H]-8-OH-DPAT as radioligand				J Med Chem 44: 418-28 (2001) BindingDB Entry DOI: 10.7270/Q22B8XBC
					More data for this Ligand-Target Pair