BDBM50102422 5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(3-phenyl-propyl)-benzamide::5-(2,5-dihydroxybenzylamino)-2-hydroxy-N-(3-phenylpropyl)benzamide::CHEMBL341946

SMILES: Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCCc2ccccc2)c1

InChI Key: InChIKey=NWPOOMNWBCXQHP-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50102422   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor erbB1 (Mus musculus)	BDBM50102422 (5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(3-pheny...) Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCCc2ccccc2)c1 Show InChI InChI=1S/C23H24N2O4/c26-19-9-11-21(27)17(13-19)15-25-18-8-10-22(28)20(14-18)23(29)24-12-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,25-28H,4,7,12,15H2,(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of epidermal growth factor receptor phosphorylation in BaF3 mouse lymphoid cells.				J Med Chem 44: 441-52 (2001) BindingDB Entry DOI: 10.7270/Q2XP746W
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50102422 (5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(3-pheny...) Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCCc2ccccc2)c1 Show InChI InChI=1S/C23H24N2O4/c26-19-9-11-21(27)17(13-19)15-25-18-8-10-22(28)20(14-18)23(29)24-12-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,25-28H,4,7,12,15H2,(H,24,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of recombinant Syk (unknown origin)				Bioorg Med Chem Lett 19: 1944-9 (2009) Article DOI: 10.1016/j.bmcl.2009.02.049 BindingDB Entry DOI: 10.7270/Q2WM1D98
					More data for this Ligand-Target Pair
Tubulin (Bos taurus)	BDBM50102422 (5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(3-pheny...) Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCCc2ccccc2)c1 Show InChI InChI=1S/C23H24N2O4/c26-19-9-11-21(27)17(13-19)15-25-18-8-10-22(28)20(14-18)23(29)24-12-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,25-28H,4,7,12,15H2,(H,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 44: 441-52 (2001) BindingDB Entry DOI: 10.7270/Q2XP746W
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50102422 (5-(2,5-Dihydroxy-benzylamino)-2-hydroxy-N-(3-pheny...) Show SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)NCCCc2ccccc2)c1 Show InChI InChI=1S/C23H24N2O4/c26-19-9-11-21(27)17(13-19)15-25-18-8-10-22(28)20(14-18)23(29)24-12-4-7-16-5-2-1-3-6-16/h1-3,5-6,8-11,13-14,25-28H,4,7,12,15H2,(H,24,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description In vitro inhibition of Syk protein tyrosine kinase				J Med Chem 44: 441-52 (2001) BindingDB Entry DOI: 10.7270/Q2XP746W
					More data for this Ligand-Target Pair