null

SMILES: COC(=O)C1=C(N)N(C2=C(C1c1cc3cc(C)ccc3n3nnnc13)C(=O)CCC2)c1cccnc1

InChI Key: InChIKey=OSPYQHKLIVOIGI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50103532 (CHEMBL3325474) Show SMILES COC(=O)C1=C(N)N(C2=C(C1c1cc3cc(C)ccc3n3nnnc13)C(=O)CCC2)c1cccnc1 |c:4,8| Show InChI InChI=1S/C26H23N7O3/c1-14-8-9-18-15(11-14)12-17(25-29-30-31-33(18)25)21-22-19(6-3-7-20(22)34)32(16-5-4-10-28-13-16)24(27)23(21)26(35)36-2/h4-5,8-13,21H,3,6-7,27H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged recombinant HER2 (unknown origin) expressed in Sf9 cells assessed as reduction in enzyme autophosphorylation by DELFIA...				Bioorg Med Chem Lett 24: 4472-6 (2014) Article DOI: 10.1016/j.bmcl.2014.07.094 BindingDB Entry DOI: 10.7270/Q2PV6N5T
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50103532 (CHEMBL3325474) Show SMILES COC(=O)C1=C(N)N(C2=C(C1c1cc3cc(C)ccc3n3nnnc13)C(=O)CCC2)c1cccnc1 |c:4,8| Show InChI InChI=1S/C26H23N7O3/c1-14-8-9-18-15(11-14)12-17(25-29-30-31-33(18)25)21-22-19(6-3-7-20(22)34)32(16-5-4-10-28-13-16)24(27)23(21)26(35)36-2/h4-5,8-13,21H,3,6-7,27H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of histidine-tagged recombinant EGFR cytoplasmic domain (amino acids 645-1186) (unknown origin) expressed in Sf9 cells assessed as reducti...				Bioorg Med Chem Lett 24: 4472-6 (2014) Article DOI: 10.1016/j.bmcl.2014.07.094 BindingDB Entry DOI: 10.7270/Q2PV6N5T
					More data for this Ligand-Target Pair