BDBM50103805 4-[2-(4-Guanidino-phenyl)-acetyl]-piperazine-1-carboxylic acid (3,3-diphenyl-propyl)-amide::CHEMBL310411

SMILES: [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#7]-[#6]-[#6]-[#6](-c2ccccc2)-c2ccccc2)cc1

InChI Key: InChIKey=DWPQXGNSQVSWNH-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103805   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50103805 (4-[2-(4-Guanidino-phenyl)-acetyl]-piperazine-1-car...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1ccc(-[#6]-[#6](=O)-[#7]-2-[#6]-[#6]-[#7](-[#6]-[#6]-2)-[#6](=O)-[#7]-[#6]-[#6]-[#6](-c2ccccc2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H34N6O2/c30-28(31)33-25-13-11-22(12-14-25)21-27(36)34-17-19-35(20-18-34)29(37)32-16-15-26(23-7-3-1-4-8-23)24-9-5-2-6-10-24/h1-14,26H,15-21H2,(H,32,37)(H4,30,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Axys Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human tryptase enzyme				Bioorg Med Chem Lett 11: 2325-30 (2001) BindingDB Entry DOI: 10.7270/Q21835S6
					More data for this Ligand-Target Pair