BDBM50103878 Acetic acid 8-allyl-2-oxo-2H-chromen-7-yl ester::CHEMBL77169

SMILES: CC(=O)Oc1ccc2ccc(=O)oc2c1CC=C

InChI Key: InChIKey=SVCVRRCALFDFGG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103878   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Steroid 5-alpha-reductase (Homo sapiens (Human))	BDBM50103878 (Acetic acid 8-allyl-2-oxo-2H-chromen-7-yl ester | ...) Show SMILES CC(=O)Oc1ccc2ccc(=O)oc2c1CC=C Show InChI InChI=1S/C14H12O4/c1-3-4-11-12(17-9(2)15)7-5-10-6-8-13(16)18-14(10)11/h3,5-8H,1,4H2,2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)				Bioorg Med Chem Lett 11: 2361-3 (2001) BindingDB Entry DOI: 10.7270/Q2RR1ZS9
					More data for this Ligand-Target Pair
5α-Reductase 1 (5α-R1) (Homo sapiens (Human))	BDBM50103878 (Acetic acid 8-allyl-2-oxo-2H-chromen-7-yl ester | ...) Show SMILES CC(=O)Oc1ccc2ccc(=O)oc2c1CC=C Show InChI InChI=1S/C14H12O4/c1-3-4-11-12(17-9(2)15)7-5-10-6-8-13(16)18-14(10)11/h3,5-8H,1,4H2,2H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibitory activity against 5-alpha-reductase type 1 in cell culture system using LNCaP cells (androgen-sensitive human prostatic cancer cell line)				Bioorg Med Chem Lett 11: 2361-3 (2001) BindingDB Entry DOI: 10.7270/Q2RR1ZS9
					More data for this Ligand-Target Pair