BDBM50104493 (R)-4-tert-Butoxycarbonylamino-4-[(R)-1-{12-[(2-chloro-phenoxy)-hydroxy-phosphoryloxy]-dodecylcarbamoyl}-2-(1H-indol-3-yl)-ethylcarbamoyl]-butyric acid; compound with triethyl-amine::CHEMBL315220

SMILES: CC(C)(C)OC(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl

InChI Key: InChIKey=FZLJJPBYINXZRZ-CZNDPXEESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50104493 ((R)-4-tert-Butoxycarbonylamino-4-[(R)-1-{12-[(2-ch...) Show SMILES CC(C)(C)OC(=O)N[C@H](CCC(O)=O)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl Show InChI InChI=1S/C39H56ClN4O10P/c1-39(2,3)53-38(49)44-32(22-23-35(45)46)37(48)43-33(26-28-27-42-31-20-14-12-18-29(28)31)36(47)41-24-16-10-8-6-4-5-7-9-11-17-25-52-55(50,51)54-34-21-15-13-19-30(34)40/h12-15,18-21,27,32-33,42H,4-11,16-17,22-26H2,1-3H3,(H,41,47)(H,43,48)(H,44,49)(H,45,46)(H,50,51)/t32-,33-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibitory activity against telomerase extracted from HCT 116 cell lines				Bioorg Med Chem Lett 11: 2581-4 (2001) BindingDB Entry DOI: 10.7270/Q2XD10Z2
					More data for this Ligand-Target Pair