BDBM50104500 2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide::2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide::BB-3554::CHEMBL84969
SMILES: CCCCC(CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C
InChI Key: InChIKey=AVDLWYHBABSSHC-ZGTCLIOFSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Matrix metalloproteinase-7 (MMP7) (Homo sapiens (Human)) | BDBM50104500 (2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
British Biotech Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-7 | Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM50104500 (2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
British Biotech Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-2 | Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptide deformylase (Escherichia coli) | BDBM50104500 (2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
The Ohio State University Curated by ChEMBL | Assay Description Inhibitory concentration against peptide deformylase was determined | J Med Chem 46: 3771-4 (2003) Article DOI: 10.1021/jm034113f BindingDB Entry DOI: 10.7270/Q2765DQ4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peptide deformylase mitochondrial (Homo sapiens (Human)) | BDBM50104500 (2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
British Biotech Pharmaceuticals Limited Curated by ChEMBL | Assay Description Antibacterial activity of the compound against E. coli Peptide deformylase. Ni | Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50104500 (2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
British Biotech Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of human Matrix metalloproteinase-1 | Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50104500 (2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
British Biotech Pharmaceuticals Limited Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-3 | Bioorg Med Chem Lett 11: 2585-8 (2001) BindingDB Entry DOI: 10.7270/Q2SN0886 | |||||||||||
More data for this Ligand-Target Pair |