BDBM50105263 2-{3-[(Amino-phenyl-methyl)-hydroxy-phosphinoyl]-2-biphenyl-4-ylmethyl-propionylamino}-propionic acid anion::CHEMBL117394

SMILES: C[C@H](NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)CP(O)(=O)[C@H]([NH3+])c1ccccc1)C([O-])=O

InChI Key: InChIKey=NCJYNTULOJIUPY-NWVWQQAFSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50105263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50105263 (2-{3-[(Amino-phenyl-methyl)-hydroxy-phosphinoyl]-2...) Show SMILES C[C@H](NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)CP(O)(=O)[C@H]([NH3+])c1ccccc1)C([O-])=O Show InChI InChI=1S/C26H29N2O5P/c1-18(26(30)31)28-25(29)23(17-34(32,33)24(27)22-10-6-3-7-11-22)16-19-12-14-21(15-13-19)20-8-4-2-5-9-20/h2-15,18,23-24H,16-17,27H2,1H3,(H,28,29)(H,30,31)(H,32,33)/t18-,23-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of enkephalin degrading enzyme, neutral endopeptidase (NEP)				J Med Chem 44: 3523-30 (2001) BindingDB Entry DOI: 10.7270/Q2QN67HK
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50105263 (2-{3-[(Amino-phenyl-methyl)-hydroxy-phosphinoyl]-2...) Show SMILES C[C@H](NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)CP(O)(=O)[C@H]([NH3+])c1ccccc1)C([O-])=O Show InChI InChI=1S/C26H29N2O5P/c1-18(26(30)31)28-25(29)23(17-34(32,33)24(27)22-10-6-3-7-11-22)16-19-12-14-21(15-13-19)20-8-4-2-5-9-20/h2-15,18,23-24H,16-17,27H2,1H3,(H,28,29)(H,30,31)(H,32,33)/t18-,23-,24-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Compound was evaluated for inhibition of enkephalin degrading enzyme, aminopeptidase N(APN)				J Med Chem 44: 3523-30 (2001) BindingDB Entry DOI: 10.7270/Q2QN67HK
					More data for this Ligand-Target Pair