null
SMILES: COc1cccc(OC)c1OC(=O)C(C)N1CCc2ccccc2C1
InChI Key: InChIKey=GHMSPLAJMQBJKD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human)) | BDBM50105786 (2-(3,4-Dihydro-1H-isoquinolin-2-yl)-propionic acid...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a |
Organon Research Curated by ChEMBL | Assay Description GABA-modulatory action compound was evaluated on Oocytes expressing recombinant human alpha-1-beta-3-gamma-2L GABA A receptor at concentrations of >=... | J Med Chem 44: 3582-91 (2001) BindingDB Entry DOI: 10.7270/Q2KW5GRD | |||||||||||
More data for this Ligand-Target Pair |