BDBM50105869 CHEMBL3597769

SMILES: Fc1ccc(NC(=O)c2ccn(n2)S(=O)(=O)c2cccc(c2)C(F)(F)F)c(Cl)c1

InChI Key: InChIKey=CBMJZNLELPFGAN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50105869   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50105869 (CHEMBL3597769) Show SMILES Fc1ccc(NC(=O)c2ccn(n2)S(=O)(=O)c2cccc(c2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C17H10ClF4N3O3S/c18-13-9-11(19)4-5-14(13)23-16(26)15-6-7-25(24-15)29(27,28)12-3-1-2-10(8-12)17(20,21)22/h1-9H,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assay				Bioorg Med Chem Lett 25: 3017-23 (2015) BindingDB Entry DOI: 10.7270/Q2F191G3
					More data for this Ligand-Target Pair
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50105869 (CHEMBL3597769) Show SMILES Fc1ccc(NC(=O)c2ccn(n2)S(=O)(=O)c2cccc(c2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C17H10ClF4N3O3S/c18-13-9-11(19)4-5-14(13)23-16(26)15-6-7-25(24-15)29(27,28)12-3-1-2-10(8-12)17(20,21)22/h1-9H,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate				Bioorg Med Chem Lett 25: 3017-23 (2015) BindingDB Entry DOI: 10.7270/Q2F191G3
					More data for this Ligand-Target Pair