BDBM50106256 1-Benzenesulfonyl-3-(2-dimethylamino-ethyl)-1H-indole-5-carbonitrile::CHEMBL127089

SMILES: CN(C)CCc1cn(c2ccc(cc12)C#N)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=GACDVHSHGYKQKO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106256   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50106256 (1-Benzenesulfonyl-3-(2-dimethylamino-ethyl)-1H-ind...) Show SMILES CN(C)CCc1cn(c2ccc(cc12)C#N)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C19H19N3O2S/c1-21(2)11-10-16-14-22(19-9-8-15(13-20)12-18(16)19)25(23,24)17-6-4-3-5-7-17/h3-9,12,14H,10-11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.				J Med Chem 44: 3881-95 (2001) BindingDB Entry DOI: 10.7270/Q2T72GRW
					More data for this Ligand-Target Pair