null

SMILES: COC1C(=N)C(=O)c2nc(ccc2C1=O)-c1nc(C(=O)OC)c(C)c(c1N)-c1ccc(OC)c(OC)c1O

InChI Key: InChIKey=XSNMOELGPPKINE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
M-phase inducer phosphatase 2 (Homo sapiens (Human))	BDBM50106491 (5-Amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydro...) Show SMILES COC1C(=N)C(=O)c2nc(ccc2C1=O)-c1nc(C(=O)OC)c(C)c(c1N)-c1ccc(OC)c(OC)c1O |(10.32,-.31,;10.33,-1.86,;11.68,-2.63,;11.68,-4.17,;10.33,-4.94,;13,-4.93,;13.01,-6.48,;14.33,-4.16,;15.67,-4.93,;17,-4.16,;16.98,-2.62,;15.65,-1.86,;14.33,-2.63,;13,-1.85,;13,-.29,;18.33,-4.93,;19.66,-4.15,;21,-4.92,;22.33,-4.15,;22.31,-2.6,;23.67,-4.91,;25,-4.12,;21,-6.46,;22.34,-7.23,;19.66,-7.25,;18.33,-6.48,;17,-7.25,;19.67,-8.79,;18.33,-9.55,;18.33,-11.09,;19.66,-11.86,;19.67,-13.41,;18.33,-14.18,;21,-11.09,;22.34,-11.85,;22.35,-13.4,;21,-9.55,;22.33,-8.78,)| Show InChI InChI=1S/C26H24N4O8/c1-10-15(11-7-9-14(35-2)24(36-3)21(11)31)16(27)20(30-18(10)26(34)38-5)13-8-6-12-19(29-13)23(33)17(28)25(37-4)22(12)32/h6-9,25,28,31H,27H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human cell division cycle 25B				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Homo sapiens (Human))	BDBM50106491 (5-Amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydro...) Show SMILES COC1C(=N)C(=O)c2nc(ccc2C1=O)-c1nc(C(=O)OC)c(C)c(c1N)-c1ccc(OC)c(OC)c1O |(10.32,-.31,;10.33,-1.86,;11.68,-2.63,;11.68,-4.17,;10.33,-4.94,;13,-4.93,;13.01,-6.48,;14.33,-4.16,;15.67,-4.93,;17,-4.16,;16.98,-2.62,;15.65,-1.86,;14.33,-2.63,;13,-1.85,;13,-.29,;18.33,-4.93,;19.66,-4.15,;21,-4.92,;22.33,-4.15,;22.31,-2.6,;23.67,-4.91,;25,-4.12,;21,-6.46,;22.34,-7.23,;19.66,-7.25,;18.33,-6.48,;17,-7.25,;19.67,-8.79,;18.33,-9.55,;18.33,-11.09,;19.66,-11.86,;19.67,-13.41,;18.33,-14.18,;21,-11.09,;22.34,-11.85,;22.35,-13.4,;21,-9.55,;22.33,-8.78,)| Show InChI InChI=1S/C26H24N4O8/c1-10-15(11-7-9-14(35-2)24(36-3)21(11)31)16(27)20(30-18(10)26(34)38-5)13-8-6-12-19(29-13)23(33)17(28)25(37-4)22(12)32/h6-9,25,28,31H,27H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory Activity against Recombinant Human VHR				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50106491 (5-Amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydro...) Show SMILES COC1C(=N)C(=O)c2nc(ccc2C1=O)-c1nc(C(=O)OC)c(C)c(c1N)-c1ccc(OC)c(OC)c1O |(10.32,-.31,;10.33,-1.86,;11.68,-2.63,;11.68,-4.17,;10.33,-4.94,;13,-4.93,;13.01,-6.48,;14.33,-4.16,;15.67,-4.93,;17,-4.16,;16.98,-2.62,;15.65,-1.86,;14.33,-2.63,;13,-1.85,;13,-.29,;18.33,-4.93,;19.66,-4.15,;21,-4.92,;22.33,-4.15,;22.31,-2.6,;23.67,-4.91,;25,-4.12,;21,-6.46,;22.34,-7.23,;19.66,-7.25,;18.33,-6.48,;17,-7.25,;19.67,-8.79,;18.33,-9.55,;18.33,-11.09,;19.66,-11.86,;19.67,-13.41,;18.33,-14.18,;21,-11.09,;22.34,-11.85,;22.35,-13.4,;21,-9.55,;22.33,-8.78,)| Show InChI InChI=1S/C26H24N4O8/c1-10-15(11-7-9-14(35-2)24(36-3)21(11)31)16(27)20(30-18(10)26(34)38-5)13-8-6-12-19(29-13)23(33)17(28)25(37-4)22(12)32/h6-9,25,28,31H,27H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibitory Activity against Recombinant Human PTP1				J Med Chem 44: 4042-9 (2001) BindingDB Entry DOI: 10.7270/Q2X34WR5
					More data for this Ligand-Target Pair