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SMILES: Cc1ccc(cc1)-c1c(Cl)c(CCl)nn1-c1ccc(cc1)S(N)(=O)=O

InChI Key: InChIKey=HGDANNJQRKVLNZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106762   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50106762 (CHEMBL3601277) Show SMILES Cc1ccc(cc1)-c1c(Cl)c(CCl)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15Cl2N3O2S/c1-11-2-4-12(5-3-11)17-16(19)15(10-18)21-22(17)13-6-8-14(9-7-13)25(20,23)24/h2-9H,10H2,1H3,(H2,20,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Dresden Curated by ChEMBL					Assay Description Inhibition of ovine COX-1 assessed as reduction of prostaglandin-G2 to prostaglandin-H2 and oxidation of 10-acetyl-3,7-dihydroxyphenoxazine to resoru...				Bioorg Med Chem Lett 25: 3295-300 (2015) BindingDB Entry DOI: 10.7270/Q23N2555
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50106762 (CHEMBL3601277) Show SMILES Cc1ccc(cc1)-c1c(Cl)c(CCl)nn1-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C17H15Cl2N3O2S/c1-11-2-4-12(5-3-11)17-16(19)15(10-18)21-22(17)13-6-8-14(9-7-13)25(20,23)24/h2-9H,10H2,1H3,(H2,20,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universitat Dresden Curated by ChEMBL					Assay Description Inhibition of recombinant human COX-2 assessed as reduction of prostaglandin-G2 to prostaglandin-H2 and oxidation of 10-acetyl-3,7-dihydroxyphenoxazi...				Bioorg Med Chem Lett 25: 3295-300 (2015) BindingDB Entry DOI: 10.7270/Q23N2555
					More data for this Ligand-Target Pair