BDBM50107795 4'-Trifluoromethyl-biphenyl-2-carboxylic acid [2-(3,3-dimethyl-ureido)-indan-5-yl]-amide::CHEMBL143647

SMILES: CN(C)C(=O)NC1Cc2ccc(NC(=O)c3ccccc3-c3ccc(cc3)C(F)(F)F)cc2C1

InChI Key: InChIKey=TZNSZZMLARSGAI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107795   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Microsomal triglyceride transfer protein (Homo sapiens (Human))	BDBM50107795 (4'-Trifluoromethyl-biphenyl-2-carboxylic acid [2-(...) Show SMILES CN(C)C(=O)NC1Cc2ccc(NC(=O)c3ccccc3-c3ccc(cc3)C(F)(F)F)cc2C1 Show InChI InChI=1S/C26H24F3N3O2/c1-32(2)25(34)31-21-13-17-9-12-20(14-18(17)15-21)30-24(33)23-6-4-3-5-22(23)16-7-10-19(11-8-16)26(27,28)29/h3-12,14,21H,13,15H2,1-2H3,(H,30,33)(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description In vitro inhibitory activity against MTP using MTP transfer assay				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair
Apolipoprotein B-100 (Homo sapiens (Human))	BDBM50107795 (4'-Trifluoromethyl-biphenyl-2-carboxylic acid [2-(...) Show SMILES CN(C)C(=O)NC1Cc2ccc(NC(=O)c3ccccc3-c3ccc(cc3)C(F)(F)F)cc2C1 Show InChI InChI=1S/C26H24F3N3O2/c1-32(2)25(34)31-21-13-17-9-12-20(14-18(17)15-21)30-24(33)23-6-4-3-5-22(23)16-7-10-19(11-8-16)26(27,28)29/h3-12,14,21H,13,15H2,1-2H3,(H,30,33)(H,31,34)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Reasearch Curated by ChEMBL					Assay Description Inhibition of apolipoprotein B (apoB) secreted by human hepatoma cells (Hep G2) at 100 nM				J Med Chem 44: 4677-87 (2001) BindingDB Entry DOI: 10.7270/Q23F4NXH
					More data for this Ligand-Target Pair