null

SMILES: CC1(C)NC(=O)N(CC(CS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)N(O)C=O)C1=O

InChI Key: InChIKey=BYBOLCACCXBYNF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50108144 (CHEMBL75154 | N-[1-(4,4-Dimethyl-2,5-dioxo-imidazo...) Show SMILES CC1(C)NC(=O)N(CC(CS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)N(O)C=O)C1=O Show InChI InChI=1S/C22H22F3N3O6S/c1-21(2)19(30)27(20(31)26-21)11-17(28(32)13-29)12-35(33,34)18-9-5-15(6-10-18)14-3-7-16(8-4-14)22(23,24)25/h3-10,13,17,32H,11-12H2,1-2H3,(H,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro selective inhibition against Matrix metalloprotease-9 (MMP-9) using fluorimetric assay				J Med Chem 45: 219-32 (2001) BindingDB Entry DOI: 10.7270/Q2XP747B
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50108144 (CHEMBL75154 | N-[1-(4,4-Dimethyl-2,5-dioxo-imidazo...) Show SMILES CC1(C)NC(=O)N(CC(CS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)N(O)C=O)C1=O Show InChI InChI=1S/C22H22F3N3O6S/c1-21(2)19(30)27(20(31)26-21)11-17(28(32)13-29)12-35(33,34)18-9-5-15(6-10-18)14-3-7-16(8-4-14)22(23,24)25/h3-10,13,17,32H,11-12H2,1-2H3,(H,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro selective inhibition against matrix metalloprotease-1 (MMP-1) using a fluorimetric assay				J Med Chem 45: 219-32 (2001) BindingDB Entry DOI: 10.7270/Q2XP747B
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50108144 (CHEMBL75154 | N-[1-(4,4-Dimethyl-2,5-dioxo-imidazo...) Show SMILES CC1(C)NC(=O)N(CC(CS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)N(O)C=O)C1=O Show InChI InChI=1S/C22H22F3N3O6S/c1-21(2)19(30)27(20(31)26-21)11-17(28(32)13-29)12-35(33,34)18-9-5-15(6-10-18)14-3-7-16(8-4-14)22(23,24)25/h3-10,13,17,32H,11-12H2,1-2H3,(H,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro selective inhibition against matrix metalloprotease-2 (MMP-2) using fluorimetric assay				J Med Chem 45: 219-32 (2001) BindingDB Entry DOI: 10.7270/Q2XP747B
					More data for this Ligand-Target Pair