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BDBM50109131 5-[1-Pyridin-3-yl-1-{3-[(2-pyridin-3-yl-thiazolidine-4-carbonyl)-amino]-phenyl}-meth-(Z)-ylideneaminooxy]-pentanoic acid ethyl ester::CHEMBL420137

SMILES: CCOC(=O)CCCCO\N=C(/c1cccnc1)c1cccc(NC(=O)C2CSC(N2)c2cccnc2)c1

InChI Key: InChIKey=SKHNUTGZUANNCI-MKFPQRGTSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50109131   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Thromboxane A2 Synthase (P450 TxA2)


(Homo sapiens (Human))		BDBM50109131
PNG
(5-[1-Pyridin-3-yl-1-{3-[(2-pyridin-3-yl-thiazolidi...)
Show SMILES CCOC(=O)CCCCO\N=C(/c1cccnc1)c1cccc(NC(=O)C2CSC(N2)c2cccnc2)c1
Show InChI InChI=1S/C28H31N5O4S/c1-2-36-25(34)12-3-4-15-37-33-26(21-9-6-13-29-17-21)20-8-5-11-23(16-20)31-27(35)24-19-38-28(32-24)22-10-7-14-30-18-22/h5-11,13-14,16-18,24,28,32H,2-4,12,15,19H2,1H3,(H,31,35)/b33-26-
KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/a 21n/an/an/an/an/an/a



Nikken Chemicals Co., Ltd.

Curated by ChEMBL


Assay Description
In vitro inhibition of TXB2 production by incubating prostaglandin H2 with human platelet microsomes.

Bioorg Med Chem Lett 12: 341-4 (2002)


BindingDB Entry DOI: 10.7270/Q2ST7P56
More data for this
Ligand-Target Pair