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SMILES: N[C@@H](Cc1o[nH]c(=O)c1-c1ccc2ccccc2c1)C(O)=O

InChI Key: InChIKey=WSJVPOMJYXGEDF-LBPRGKRZSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50109656 (2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...) Show SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1ccc2ccccc2c1)C(O)=O Show InChI InChI=1S/C16H14N2O4/c17-12(16(20)21)8-13-14(15(19)18-22-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8,17H2,(H,18,19)(H,20,21)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 5 using established second messenger assay systems.				J Med Chem 45: 988-91 (2002) BindingDB Entry DOI: 10.7270/Q2M32V27
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50109656 (2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...) Show SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1ccc2ccccc2c1)C(O)=O Show InChI InChI=1S/C16H14N2O4/c17-12(16(20)21)8-13-14(15(19)18-22-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8,17H2,(H,18,19)(H,20,21)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.49E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 1 using established second messenger assay systems.				J Med Chem 45: 988-91 (2002) BindingDB Entry DOI: 10.7270/Q2M32V27
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50109656 (2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...) Show SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1ccc2ccccc2c1)C(O)=O Show InChI InChI=1S/C16H14N2O4/c17-12(16(20)21)8-13-14(15(19)18-22-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8,17H2,(H,18,19)(H,20,21)/t12-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 2 using established second messenger assay systems.				J Med Chem 45: 988-91 (2002) BindingDB Entry DOI: 10.7270/Q2M32V27
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50109656 (2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...) Show SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1ccc2ccccc2c1)C(O)=O Show InChI InChI=1S/C16H14N2O4/c17-12(16(20)21)8-13-14(15(19)18-22-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8,17H2,(H,18,19)(H,20,21)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description The compound was tested for the receptor binding affinity at Metabotropic glutamate receptor 4 using established second messenger assay systems.				J Med Chem 45: 988-91 (2002) BindingDB Entry DOI: 10.7270/Q2M32V27
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, kainate 1 (RAT)	BDBM50109656 (2-Amino-3-(3-hydroxy-4-naphthalen-2-yl-isoxazol-5-...) Show SMILES N[C@@H](Cc1o[nH]c(=O)c1-c1ccc2ccccc2c1)C(O)=O Show InChI InChI=1S/C16H14N2O4/c17-12(16(20)21)8-13-14(15(19)18-22-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8,17H2,(H,18,19)(H,20,21)/t12-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Concentration of the compound which causes 50% reduction in receptor binding affinity against Ionotropic glutamate receptor ionotropic kainate using ...				J Med Chem 45: 988-91 (2002) BindingDB Entry DOI: 10.7270/Q2M32V27
					More data for this Ligand-Target Pair