null
SMILES: NC(=N)c1ccc(CNC(=O)CNC(=O)[C@@H](CO)NS(=O)(=O)CCc2ccccc2)cc1
InChI Key: InChIKey=UIEFTXMHYNHGEZ-GOSISDBHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM50110010 (CHEMBL415741 | N-[(4-Carbamimidoyl-benzylcarbamoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jena Curated by ChEMBL | Assay Description In vitro inhibition of plasminogen activator urokinase. | Bioorg Med Chem Lett 12: 645-8 (2002) BindingDB Entry DOI: 10.7270/Q2NZ86XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Homo sapiens (Human)) | BDBM50110010 (CHEMBL415741 | N-[(4-Carbamimidoyl-benzylcarbamoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jena Curated by ChEMBL | Assay Description In vitro inhibition of trypsin. | Bioorg Med Chem Lett 12: 645-8 (2002) BindingDB Entry DOI: 10.7270/Q2NZ86XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50110010 (CHEMBL415741 | N-[(4-Carbamimidoyl-benzylcarbamoyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jena Curated by ChEMBL | Assay Description In vitro inhibition of Coagulation factor Xa. | Bioorg Med Chem Lett 12: 645-8 (2002) BindingDB Entry DOI: 10.7270/Q2NZ86XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50110010 (CHEMBL415741 | N-[(4-Carbamimidoyl-benzylcarbamoyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jena Curated by ChEMBL | Assay Description In vitro inhibition of thrombin. | Bioorg Med Chem Lett 12: 645-8 (2002) BindingDB Entry DOI: 10.7270/Q2NZ86XS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50110010 (CHEMBL415741 | N-[(4-Carbamimidoyl-benzylcarbamoyl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universitat Jena Curated by ChEMBL | Assay Description In vitro inhibition of Plasmin. | Bioorg Med Chem Lett 12: 645-8 (2002) BindingDB Entry DOI: 10.7270/Q2NZ86XS | |||||||||||
More data for this Ligand-Target Pair |