BDBM50110480 CHEMBL166156::[1-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-pyrazol-3-yl]-methanol

SMILES: CS(=O)(=O)c1ccc(cc1)-n1nc(CO)cc1-c1ccccc1

InChI Key: InChIKey=AKYAXJLSWCRMRL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50110480 (CHEMBL166156 | [1-(4-Methanesulfonyl-phenyl)-5-phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(CO)cc1-c1ccccc1 Show InChI InChI=1S/C17H16N2O3S/c1-23(21,22)16-9-7-15(8-10-16)19-17(11-14(12-20)18-19)13-5-3-2-4-6-13/h2-11,20H,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoires Innothera Curated by ChEMBL					Assay Description The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 1 using monocytes-like cells				Bioorg Med Chem Lett 12: 779-82 (2002) BindingDB Entry DOI: 10.7270/Q20864MC
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50110480 (CHEMBL166156 | [1-(4-Methanesulfonyl-phenyl)-5-phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(CO)cc1-c1ccccc1 Show InChI InChI=1S/C17H16N2O3S/c1-23(21,22)16-9-7-15(8-10-16)19-17(11-14(12-20)18-19)13-5-3-2-4-6-13/h2-11,20H,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoires Innothera Curated by ChEMBL					Assay Description The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 2 using osteosarcomes cells				Bioorg Med Chem Lett 12: 779-82 (2002) BindingDB Entry DOI: 10.7270/Q20864MC
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50110480 (CHEMBL166156 | [1-(4-Methanesulfonyl-phenyl)-5-phe...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(CO)cc1-c1ccccc1 Show InChI InChI=1S/C17H16N2O3S/c1-23(21,22)16-9-7-15(8-10-16)19-17(11-14(12-20)18-19)13-5-3-2-4-6-13/h2-11,20H,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoires Innothera Curated by ChEMBL					Assay Description The compound was evaluated for its inhibitory activity against 5-lipoxygenase using granulocytes-type cells				Bioorg Med Chem Lett 12: 779-82 (2002) BindingDB Entry DOI: 10.7270/Q20864MC
					More data for this Ligand-Target Pair