BDBM50110486 3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-pyrazole::CHEMBL165946

SMILES: CCCCc1cc(-c2ccccc2)n(n1)-c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=UYTGVWPXYLXVSF-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50110486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50110486 (3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-p...) Show SMILES CCCCc1cc(-c2ccccc2)n(n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C20H22N2O2S/c1-3-4-10-17-15-20(16-8-6-5-7-9-16)22(21-17)18-11-13-19(14-12-18)25(2,23)24/h5-9,11-15H,3-4,10H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoires Innothera Curated by ChEMBL					Assay Description The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 1 using monocytes-like cells				Bioorg Med Chem Lett 12: 779-82 (2002) BindingDB Entry DOI: 10.7270/Q20864MC
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50110486 (3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-p...) Show SMILES CCCCc1cc(-c2ccccc2)n(n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C20H22N2O2S/c1-3-4-10-17-15-20(16-8-6-5-7-9-16)22(21-17)18-11-13-19(14-12-18)25(2,23)24/h5-9,11-15H,3-4,10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoires Innothera Curated by ChEMBL					Assay Description The compound was evaluated for its inhibitory activity against 5-lipoxygenase using granulocytes-type cells				Bioorg Med Chem Lett 12: 779-82 (2002) BindingDB Entry DOI: 10.7270/Q20864MC
					More data for this Ligand-Target Pair
Cyclooxygenase (Homo sapiens (Human))	BDBM50110486 (3-Butyl-1-(4-methanesulfonyl-phenyl)-5-phenyl-1H-p...) Show SMILES CCCCc1cc(-c2ccccc2)n(n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C20H22N2O2S/c1-3-4-10-17-15-20(16-8-6-5-7-9-16)22(21-17)18-11-13-19(14-12-18)25(2,23)24/h5-9,11-15H,3-4,10H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoires Innothera Curated by ChEMBL					Assay Description The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 2 using osteosarcomes cells				Bioorg Med Chem Lett 12: 779-82 (2002) BindingDB Entry DOI: 10.7270/Q20864MC
					More data for this Ligand-Target Pair