BDBM50110503 6-(3-Chloro-4-fluoro-phenyl)-2,4,4-trimethyl-1,4-dihydro-2H-benzo[d][1,3]oxazine::CHEMBL164908
SMILES: CC1Nc2ccc(cc2C(C)(C)O1)-c1ccc(F)c(Cl)c1
InChI Key: InChIKey=LPXGYQQVIMWYFD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Progesterone receptor (Homo sapiens (Human)) | BDBM50110503 (6-(3-Chloro-4-fluoro-phenyl)-2,4,4-trimethyl-1,4-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 213 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity against progesterone receptor using human T47D breast carcinoma cell line | Bioorg Med Chem Lett 12: 787-90 (2002) BindingDB Entry DOI: 10.7270/Q2WS8TSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Progesterone receptor (Homo sapiens (Human)) | BDBM50110503 (6-(3-Chloro-4-fluoro-phenyl)-2,4,4-trimethyl-1,4-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Binding affinity against progesterone receptor using human T47D breast carcinoma cell line | Bioorg Med Chem Lett 12: 787-90 (2002) BindingDB Entry DOI: 10.7270/Q2WS8TSW | |||||||||||
More data for this Ligand-Target Pair |